The invention relates to an anti-infection and anti-blood coagulation central venous catheter. The anti-infection and anti-blood coagulation central venous catheter comprises a catheter body, a tip end and a connecting base, wherein the catheter body is uniformly loaded with an anti-infection medicine and comprises an inner catheter and an outer catheter; a gap is formed between the inner catheterand the outer catheter, is of a sealing structure, and is filled with a supersaturated sodium aliphatate solution; the exterior of the catheter body is coated with a layer of 3M Thinsulate high-efficiency warming velvet. The anti-infection and anti-blood coagulation central venous catheter has the beneficial effects that the anti-infection medicine is loaded into the catheter by a solvent, so that the anti-infection property of the catheter is improved; the supersaturated sodium aliphatate solution is filled between the outer catheter and the inner catheter, and is heated to increase the temperature, the coated 3M Thinsulate high-efficiency warming velvet is used for insulating heat, and the 3M Thinsulate high-efficiency warming velvet has long heat insulating time and good effect, so that the coagulation of blood in the in-vitro catheter is avoided.