The invention discloses a five-section mixing-type three-dimensional wound iron core. The core comprises three single-phase iron cores with the same structure. Each single-phase iron core comprises two iron core columns and two iron yokes. The two iron core columns are arranged in a bilateral symmetry manner. The two iron yokes are arranged in a longitudinal symmetry manner. Each single-phase ironcore is connected with two other single-phase iron cores through iron core columns. Each single-phase iron core is formed by winding of four sections of silicon steel strips connected end to end anda section of amorphous alloy strip. One section of amorphous alloy winds at the middle position close to each single-phase iron core. The four sections of silicon steel strips respectively wind innerand outer layers of amorphous alloy strips. Each single-phase iron core further comprises a rectangular amorphous alloy gasket. With the five-section mixing-type three-dimensional wound iron core, no-load loss of a transformer is further lowered while noise is reduced and cost of copper and iron is saved.