The invention discloses a grape planting method by comprehensive use of flue-cured tobacco nursery nutrition fluid and shed, which includes steps of building 3 underground pits at the bottom part of every nursery pond at equal space; plastering four sides and the bottom part by cement to ensure no water leakage; reserving a water draining pipe at the place with 1 m height to the bottom part of thepond base, and connecting the water draining pipe with a sewage pond at outside of the shed; backfilling the underground pit by soil and waste and old nursery matrix until being leveled to a nurserybed; after finishing the flue-cured tobacco nursery, collecting the waste nursery nutrition fluid in the underground pit, and cutting grape branches in the underground pit; building a guardrail by taking every grape as the center; after survival, pulling the grape vine to a sunshade screen in the shed to grow, thereby avoiding the influence of the grape growth on the flue-cured tobacco nursery; cultivating and managing according to regular grape. The method cultivates the grape by floating nursery nutrition fluid, recycles waste material, and avoids the shortcoming of eutrophication water pollution of the water body nearby by direct discharge, resource waste and environment pollution of surrounding water body.