The invention discloses a portable variable releasing bottle. The bottle comprises a bottle body, a bottle cap, a medicine well and a control component, wherein the bottle body is a round-corner cuboid; a bottle mouth is formed in the bottle body; the bottle cap can be opened or cover the bottle mouth; a pill dropping mouth is arranged in the bottle body; the medicine well is fixedly arranged in the bottle body; a through hole is formed in the medicine well; one end of the through hole is communicated with the pill dropping mouth; the other end of the through hole is communicated with the bottle mouth; the control component is arranged at the middle part of the medicine well and used for controlling the opening or the closing of the through hole; and the diameter of the through hole is greater than that of a pill. According to the bottle disclosed by the invention, only one pill can be accommodated between a first insert foot and a second insert foot of a control frame and the first insert foot and the second insert foot are alternately inserted into the through hole to alternately open or close the through hole; after the bottle body is inverted, every time a button is pressed, one pill can be taken out and if a plurality of pills are needed, the button is only needed to be pressed corresponding times, exact quantity of pills can be taken out; and therefore, the bottle has thebeneficial effects of being simple, convenient and quick in operation.