The invention discloses a structure health monitoring system based on a wireless sensing network and multiagent cooperation. The structure health monitoring system based on wireless sensing network and multiagent cooperation comprises a central management layer and a local monitoring layer. The central management layer is connected to the local monitoring layer through a gateway. The local monitoring layer comprises a plurality of local monitoring units and each local monitoring unit is in wireless connection with the gateway through an Sink node. The local monitoring unit consists of a plurality of monitoring subunits. The monitoring subunit comprises a sensing main body, a data processing main body, a damage assessment main body and a wireless transmit-receive main body. The central management layer comprises an information fusion main body, a central coordinating main body and a user interface main body. The gateway is in wireless communication with the information fusion main bodyand the central coordination main body. The information fusion main body and the central coordination main body are in communication with the user interface main body. The structure health monitoringsystem based on the wireless sensing network and multiagent cooperation realizes large area online monitoring on a structure through a multi-agent coordinating parallel distribution structure and fusing information of multiple kinds of sensors and structure state evaluation results.