The invention discloses a ultrasonic vibration high-speed electric main shaft. The ultrasonic vibration high-speed electric main shaft comprises a main shaft shell, a mandrel, a rotating joint, a magnetic steel power supply device, a transducer and a cutter; the mandrel is pivoted into the main shaft shell; the rotating joint and the transducer are respectively fixed at two ends of the mandrel; the magnetic steel power supply device is connected with the transducer through an electric conducting module; the cutter is mounted on the transducer; the cutter, the transducer, the mandrel and the rotating joint are all of hollow structures, and communicate to form a center cooling liquid conveying channel; and a cooling circulating channel is formed on the main shaft shell. The ultrasonic vibration high-speed electric main shaft can improve the cooling efficiency, can prevent the carbon powder pollution caused by contact electric conduction of the transducer, and facilitates reduction of themaintenance cost.