The invention relates to an amide compound, and a preparation method and an application thereof, belonging to the technical field of organic macromolecular compounds. The amide compound is directly added into an organic material as an antioxidant and a slipping agent, wherein the addition amount of the amide compound accounts for 0.01 wt% to 10 wt% of the amount of the organic material. The amidecompound provided by the invention is applied as an additive of the organic material, and has dual functions of antioxidation and smoothness at the same time; and the plastic added with the amide compound has good fluidity, good heat resistance, and insusceptibility to discoloration at a high temperature, so the stability of the material can be well improved.