The invention relates to a heat exchange device for ice slurry generation and an ice slurry generation method. The heat exchange device comprises a cylinder body, a first fixing plate, a second fixingplate, heat exchange pipes and a first seal head. The first fixing plate and the second fixing plate are arranged on the inner side wall of the cylinder body in parallel in a spaced mode and define acavity with the inner side wall of the cylinder body. The first seal head is arranged at the end, close to the first fixing plate, of the cylinder body, and a first inlet and a second inlet which areused for communicating with a water inlet pipe are formed in the side wall of the end, close to the first fixing plate, of the cylinder body or the first seal head. According to the heat exchange device for ice slurry generation, compressed air in a compressed air pipe is led into the cylinder body through the second inlet to enter the heat exchange pipes, the vortex and cavity phenomena are formed on the wall faces of the inner sides of the heat exchange pipes, ice particles formed on the wall faces of the inner sides of the heat exchange pipes are torn, the situation that an ice layer is formed to increase heat transfer heat resistance is avoided, the ice layer is prevented from being formed to block the inner walls of the heat exchange pipes, the heat exchange efficiency is improved, and the ice slurry generation efficiency is improved.