The invention provides a display driving method and device. The method comprises steps of firstly measuring pulse widths of grid electrode driving signals during acquisition of optimal charging rate in multiple measurement positions of different pixel lines in a corresponding display panel; then, according to the pulse widths of the grid electrode driving signals during the acquisition of the optimal charging rate in the measurement positions, through linear interpolation, obtaining pulse widths of grid electrode driving signals during acquisition of optimal charging rate in other measurementpositions in the display panel; and finally, by use of the pulse width of the grid electrode driving signal during the acquisition of the optimal charging rate in each measurement position in the display panel obtained through the measurement and the linear interpolation, driving the display panel to work. Thus, charging uniformity of the display panel can be improved and a color cast problem is overcome.