The invention relates to a multifunctional cotton ball and medicine liquid integrated box and effectively solves the problems that many devices are used when cotton balls are used for disinfecting a wound and are easy to collide and the operation is inconvenient and unsanitary; the technical scheme to be solved is that the multifunctional cotton ball and medicine liquid integrated box comprises afirst box body, wherein a cotton ball box is arranged in the first box body, medicine storage boxes are arranged on the two sides of the cotton ball box, a support rod is arranged in the first box body, a disc and a shifting plate are arranged on the support rod, blind holes are uniformly distributed in the periphery of the shifting plate, dowels are arranged in the blind holes, inclined surfacesare arranged on the dowels, a first rack is arranged in the first box body and connected with a second rack after gear wheel reversing, through holes are formed in panels, shifting rods are hinged onthe panels, the racks drive the shifting rods to rotate, second box bodies are arranged at the upper ends of the shifting rods, and medicine applying devices are arranged in the second box bodies; according to the multifunctional cotton ball and medicine liquid integrated box, the practicability is high, the structure is ingenious, cross infection caused by continuous liquid dipping is avoided, the safety and the hygiene are improved, a medicine bottle and the cotton balls are integrated into one device, and the integrated box is convenient to carry and easy to use.