The invention relates to a DMC (dimethyl carbonate) production method and mainly solves the problems that heterogeneous catalysts are poor in activity and stability and active components are lost easily in the prior art. The method comprises the step of contacting ethylene carbonate and methanol with a catalyst under the transesterification condition, wherein the catalyst comprises at least one component AA of amino acid, lysine, arginine, histidine, alanine, glycine, glutamic acid, tryptophan and aspartic acid and at least one component HPA of phosphotungstic acid, silicotungstic acid, germanotungtic acid, arsenowolframic acid, phosphomolybdic acid, silicomolybdic acid, germanomolybdic acid and arsenomolybdic acid; the weight ratio of AA to HPA is 1/40-1/4. The problems are better solvedwith the adoption of the technical scheme, and the method can be applied to industrial production of preparation of DMC through exchange of ethylene carbonate and methanol.