The invention relates to a high-performance liquid chromatographic method for tazobactam diphenylmethyl ester serving as an intermediate product of tazobactam, and belongs to the field of chemical detection. High-performance liquid chromatographic conditions are as follows: a chromatographic column adopts the chromatographic column C18; a flowing phase is an acetonitrile-monopotassium phosphate buffer solution; the flow speed is 0.8 to 1.3 ml/min; the column temperature is 25 to 35 DEG C; a detector has a wavelength of 225 to 235 nm; the sample injection volume is 20 [mu]L; a gradient elutionmethod is adopted. The content of the tazobactam diphenylmethyl ester has a good linear relation within a concentration range of 0.2 to 1.0 mg/ml, and a correlation coefficient is 0.9998; standard correction is carried out by adopting a method of matching a blank matrix with a standard solution, so that the average recycling rate of the tazobactam diphenylmethyl ester is 90 percent or above, and arelative standard deviation is less than 2.0 percent. The method is simple and convenient to operate, high in peak shape, accurate and reliable in data and high in reproducibility.