The invention discloses an electric power system monitoring personnel simulation training all-in-one machine, which comprises an operation screen cabinet. A front screen wall of the operation screen cabinet is equipped with a power supply grid formed by a plurality of insert blocks; and a back screen wall of the operation screen cabinet is equipped with a signal acquisition module and a signal output module electrically connected with the corresponding insert blocks. The all-in-one machine also comprises a server electrically connected with the output end of the signal acquisition module and the input end of the signal output module. The communication end of the server is connected with a data bus. The data bus is electrically connected with a five-prevention work station, a monitoring work station and an evaluation work station. The all-in-one machine realizes functions of electric skill training, check and evaluation and the like, has a learning-using direct on-the-job training effect, saves training cost and improves device and personnel safety and is simple to operate.