The invention relates to a hollow fiber membrane contactor and an application thereof. The hollow fiber membrane contactor comprises hollow fiber membrane filaments which are specifically braided andfill a shell of an assembly to form a membrane contactor, wherein the hollow fiber membrane filaments in the membrane contactor are significantly improved in distribution uniformity through braiding;the adverse effects like channeling, short circuit and dead zone of a shell pass fluid are eliminated; a significant reinforcing effect can be exerted on the mass transfer effect of the membrane contactor; meanwhile, the filling rate of membrane filaments, i.e., the contact area of the membrane contactor can not be reduced. The hollow fiber membrane contactor provided by the invention can be applied to the processes of gas absorption, absorbent regeneration, membrane distillation, ammonia nitrogen wastewater treatment, etc.