The invention discloses a printed light-emitting display and a fabrication method thereof. The printed light-emitting display comprises a substrate, a driving circuit, patterned pixel electrodes, first pixel regional layers, second pixel regional layers, light-emitting layers and top electrodes, wherein a TFT array is arranged on the substrate, the driving circuit and a plurality of patterned pixel electrodes are arranged on an upper surface of the substrate, the first pixel regional layers are arranged on the upper surface of the substrate and cover an edge of each patterned pixel electrode,the second pixel regional layers are arranged above the first pixel regional layers, ink deposition regions are encircled by the second pixel regional layers adjacent to sub-pixels with different colors, the width and the height of the second pixel regional layer adjacent to the sub-pixels with different colors are respectively larger than the width and the height of the second pixel regional layer adjacent to the sub-pixel with the same color, each light-emitting layer is arranged in each ink deposition region, and the top electrodes are deposited on upper surfaces of the light-emitting layers. The printed light-emitting display is high in resolution and good in interference resistance.