The invention discloses a transfer joint structure of a hand brake. The transfer joint structure is installed on a frame and comprises hand brake operation parts, brake locking parts, clamping assemblies, first steel wires and second steel wires. The brake locking parts are installed on back wheels of the frame. The clamping assemblies comprise first clamping parts and second clamping parts. The first clamping parts and the second clamping parts are movably installed on the frame. Two ends of each first steel wire are connected with each hand brake operation part and each first clamping part.Two ends of each second steel wire are connected with each second clamping part and each brake locking part. Each hand brake operation part is operated to perform brake motion and drives each first clamping part to perform motion through each first steel wire. Each first clamping part moves to be clamped with each second clamping part and drives each second clamping part to perform motion. Each second clamping part drives each brake locking part to brake through each second steel wire. Brake steel wires are divided into a first steel wire and a second steel wire. Transfer joint of the steel wires is achieved through the clamp assemblies. Therefore, steel wires of a hand brake are convenient to assemble. The hand brake can be used for a foldable frame. The invention further discloses the frame.