The invention discloses the technical field of integrated circuits and particularly relates to a driving signal generation circuit and method and a display system. The driving signal generation circuit comprises a first comparator and an operational circuit, wherein the first comparator is used for making comparison on an initial signal and a first input signal with a preset level so as to generate a comparison signal; and the operational circuit is used for executing or operating the comparison signal and an original driving signal, so as to generate a target driving signal. According to thedriving signal generation circuit, the phenomenon that a target driving signal acting on a power supply signal end in a GOA framework is abnormal is avoided, and furthermore, a screen scanning phenomenon of the display system is avoided.