The invention relates to a device and a method for removing VOCs (volatile organic compounds) by jointly using electrostatic dedusting and plasma for a paint factory, and belongs to the technical field of power source and atmosphere environment protection. The device comprises a three-phase power source, a direct current power source, a pulse power source and a novel reactor, wherein the three-phase power source is used for supplying power for the novel reactor through the direct current power source and the pulse power source; the novel reactor comprises an electrostatic dedusting module, a medium blocking module, an LED (light emitting diode) ultraviolet light lamp module and an outer casing, and the electrodes of the electrostatic dedusting module, the medium blocking module and the LEDultraviolet light lamp module are connected in series. The method comprises the following steps of performing corona discharging to collect large-particle size dust, enabling the medium blocking module to generate low-temperature plasma, and generating complicated reaction with VOCs gas to generate CO2 (carbon dioxide) and H2O (water), so as to reach the purpose of degrading the VOCs; enabling anLED ultraviolet light lamp to radiate and transmit high-energy photons, using the high-energy photons and ozone to decompose the VOCs gas, and removing the VOCs in the gas which circulates in the intermediate electrode. The device and the method have the advantages that the dust and the VOCs gas can be effectively removed, the power consumption amount is low, the working is lasting, and the maintenance is convenient; by additionally arranging the LED ultraviolet light lamp in the later stage, the degrading efficiency is greatly improved, and the national standard is reached.