The invention relates to a novel pill jetting and drying device for medicine preparation. The novel pill jetting and drying device comprises a base fixed on the ground, an anti-blocking device and a pill jetting and drying device body and is characterized in that the anti-blocking device comprises an anti-blocking shell, a liquid medicine permeation screen is arranged in a liquid medicine permeation space, the pill jetting and drying device body mainly comprises a drying box, a heating block is arranged at the bottommost position of a heating area, a rotating machine is arranged below the drying box, a force accumulation mechanism is arranged at one end of a rotary shaft in the rotating machine, a blowing mechanism is arranged at one end of a transmission rod, and the drying box is provided with a ventilation hole. The novel pill jetting and drying device has the advantages that liquid medicine is input through devices such as a liquid pump, the liquid medicine is filtered through theanti-blocking device, the sprayers in the heating area spray the liquid medicine to breathable forming plates, air enters under the blowing effect of a blower below, and the air is heated and filteredto accelerate pill drying; in addition, the device is provided with the force accumulation mechanism which can increase the blowing speed of the blowing mechanism so as to increase air speed and accelerate pill drying.