The invention discloses an explosion suppression and pressure releasing device capable of being repeatedly used, and belongs to the technical field of pressure bearing equipment safety devices in which explosion risks exist. The device comprises an explosion venting sheet, an explosion venting cavity, an explosion suppression agent spraying system, a fire retardance layer, a flame sensor and a sprayer. The explosion venting sheet is connected with the explosion venting cavity through a sealing ring. The sprayer is arranged in the explosion venting cavity, and the bottom of the sprayer is connected with a pipeline. The fire retardance layer comprises an elastic nonmetal fire retardance wire net and a metal fire retardance wire net, and is used for extinguishing flames and absorbing and releasing explosion overpressure. A nonmetal wire net material is adopted in the elastic nonmetal fire retardance wire net so that elasticity can be achieved. When explosion venting pressure passes, the hole diameter of the wire net is enlarged, meshes are prevented from being blocked by dust, the device weight is reduced, and the metal fire retardance wire net is made of a stainless steel wire net material. The fire retardance layer and the explosion venting sheet can be replaced, and the device can be repeatedly used. The explosion suppression agent spraying system can spray different kinds of explosion suppression agents, and is suitable for explosion suppression of different materials (gas, dust and the like). The device is convenient to mount and dismount and high in applicability.