The invention discloses a blocking removal construction process for removing barium strontium calcium compound scale pollution. The process includes the steps: scale removal and blocking removal reverse replacement; clear water reverse replacement; soaking and dissolving; clear water positive extruding; scale removal and blocking removal liquid positive extruding; clear water reverse extruding. According to the process, blocking of near-well-bore areas is removed, pollution caused by inorganic scales such as barium sulfate, strontium sulfate and calcium sulfate with difficultly-dissolved acidis effectively removed by the aid of a non-acid blocking removal liquid system, oil and gas recovery efficiency is improved, blocking of formation pore throat channels can be effectively removed, water injection rate is increased, water injection pressure is reduced, and a foundation is laid for subsequent improvement of oil and gas recovery efficiency.