The invention discloses a toughening-modified epoxy resin microsphere material, and belongs to the technical field of an epoxy resin. A phase-inversion emulsion polymerisation method is adopted, a toughening monomer which is good in flexibility and good in high and low temperature resistance is added to an epoxy resin curing system in situ, and the micron modified epoxy resin microsphere materialis prepared in one step. The microsphere is good in flexibility and excellent in anti-aging performance and mechanical properties, and has bright application prospects.