The invention belongs to the technical field of fuel cells, and discloses a novel sacrificial fuel cell, a production method thereof, and an application thereof in carbon dioxide reuse through a paired synthesis method. The novel sacrificial fuel cell is obtained through constructing a sodium sulfide-oxygen fuel cell with TiO2 modified indium tin oxide as an anode and Pt-Cu2O as a cathode and catalytically reducing carbon dioxide on the cathode, and the self electric energy of the novel sacrificial fuel cell is consumed to achieve the carbon dioxide reduction purpose. The application of the novel sacrificial fuel cell in the carbon dioxide reuse through the paired synthesis method has the characteristics of simplicity in operation, environmental protection, safety, and consumption of the self electric energy of the fuel cell, and converts the carbon dioxide into an organic fuel.