The invention discloses a power generation simulation method giving consideration to multiple spatial and temporal distribution characteristics of renewable energy sources and loads. The method comprises the steps: considering the spatial and temporal distribution characteristics of renewable energy sources and loads, and forming 16 scene combinations: four seasons, workdays and rest days, and dayand night, and considering the spatial correlation of the renewable energy sources and loads; considering a self-correlation coefficient of the renewable energy sources and loads, and obtaining the distribution parameters of the renewable energy sources and loads in each scene through a Pair Copula and a Quasi-Monte Carlo sampling method; and carrying out the electricity shortage cost calculationunder the N-1 fault conditions when the multiple spatial and temporal distribution characteristics of renewable energy sources and loads are considered. The method gives consideration to the distribution characteristics and spatial correlation of the renewable energy sources and loads in different scenes, reduces the calculation errors caused by different scenes and the spatial correlation, enables the power production simulation to be more precise, and can provide instructive advice for a power grid planning worker for the power production simulation.