The invention relates to the technical field of down feather processing, in particular to a sterilization detergent for down feather. The sterilization detergent for the down feather is prepared fromthe following components in parts by weight: 12-15 parts of LAS-ammonium salt, 6-11 parts of fatty acid methyl ester ethoxylate, 6-10 parts of geranium, 6-10 parts of ethyl acetate, 3-7 parts of sodium dodecylbenzene sulfonate, 3-7 parts of lemon juice, 4-8 parts of sophorolipid, 2-4 parts of sodium persulfate, 2-3 parts of aminomethyl propanol, 6-10 parts of citric acid grass, 2-6 parts of cassiatwig, 2-4 parts of saponin, 1-2 parts of potassium pyrophosphate, 1-2 parts of poly(methylphenylsiloxane), 2-4 of maleic anhydride modified polyethylene and the like. The sterilization detergent forthe down feather has the advantages that odor is removed thoroughly, little water is used, sterilization effect is good, cleaning efficiency is high, besides, the down leather cannot be damaged whilethe odor is removed by cleaning, and breeding of bacteria after the down feather is cleaned can be reduced.