The invention belongs to the technical field of gas extraction coal mine grouting and hole sealing, andparticularly relates to a reusable bladder bag type mining grouting hole packer and a grouting method thereof. In order to reducecosts of single-hole hole sealing as much as possible under the condition that the quality of extraction, hole drilling and hole sealing is ensured, the method utilizesan original'two sealing and one grouting' bladder type grouting and hole sealing device, and innovatively distinguishes the functions oftwo bladders, a water-injection bladderwhich plays a long-termsealing role through grouting is filled with water toswell forsealing, and a grouting bladder is still sealed by grouting to swell. Simultaneously an isolation membrane is installed between ahole sealing section and the water-injection bladder, after the water-injectionbladder is filled with water, and the insulation membrane is fixed between the water-injection bladder and the inner wall of a drilling hole under the inflation action of the water-injection bladder. When a grouting section conducts grouting, a slurry is completely isolated from the water-injection bladder under the effects of the isolation membrane, thereby ensuring the smooth recycle of the water-injection bladder, andcosts of hole sealing are reduced.