The invention relates to a temperature control industrial constant temperature machine with a spherical pressure relief valve. The temperature control industrial constant temperature machine with thespherical pressure relief valve is characterized by comprising a hydraulic oil conveying pipeline which is sequentially provided with a hydraulic oil conveying pipeline conveying pump, a cooler, a heat exchanging device and a pipe type heater between a hydraulic oil inlet and a hydraulic oil outlet; a heat exchanging pipeline is connected between an upper heat exchanging connection port and a lower heat exchanging connection port of the heat exchanging device, and is provided with a gas-liquid separator, a compressor, a condenser, a heat exchanging pipeline bypass valve, a four-way valve, a first one-way valve, a first liquid storing device, a first drying filter, a first heat exchanging pipeline electromagnetic valve, a first throttling device, a second one-way valve, a second liquid storing device, a second drying filter, a second heat exchanging pipeline electromagnetic valve and a second throttling device; and the spherical pressure relief valve is arranged on an oil way at the twoends of the cooler in parallel. The temperature control industrial constant temperature machine with the spherical pressure relief valve has the beneficial effects of being high in reliability degree, not prone to damage and capable of guaranteeing stable running of the system.