The invention discloses a granular activated coke regeneration set heating pipe seal device. The granular activated coke regeneration set heating pipe seal device is mounted on a heating pipe and a draught box and comprises a moving seal ring, a steel friction ring and adjusting screw rods. The moving seal ring comprises an annular seal body which externally sleeves the heating pipe, a plurality of telescopic guide rails are uniformly fixed to the seal body, and a compression spring sleeves each telescopic air cylinder. The steel friction ring is in an annular structure and sleeves the end ofthe heating pipe, the adjusting screw rods are mounted on a supporting frame of the heating pipe and positioned on the outer side of the steel friction ring, and the steel friction ring is movably mounted on the adjusting screw rods and fixedly mounted on the draught box. The problem of poor airtightness of granular activated coke regeneration set heating pipes can be solved, and possible explosion risks caused by poor airtightness in a production process are reduced.