A cartridge for a secondary battery according to the present invention comprises: a main frame which is formed by at least four unit frames having both ends connected to each other, and is configuredto be able to be stacked on top of one another in upward and downward directions, wherein a cavity is formed inside the unit frames, and at least some of the unit frames have a horizontally penetrating opening; an upper cooling plate which is formed in the shape of a plate, and is disposed so as to cover the cavity, wherein an upper bonding unit forming an edge is bonded to the main frame; a lowercooling plate which is formed in the shape of a plate, and is spaced apart from the upper cooling plate by a fixed distance while facing the upper cooling plate such that a cooling channel is formedbetween the lower cooling plate and the upper cooling plate, wherein a lower bonding unit forming an edge is bonded to the main frame. Specifically, the main frame comprises: an upper groove which hasa body recessed along a peripheral direction of the main frame, and is filled with an adhesive; a lower groove which is disposed below the upper groove, is formed in a shape symmetric to the upper groove, and is filled with an adhesive, wherein the upper bonding unit is bonded and fixed to the upper groove, and the lower bonding unit is bonded and fixed to the lower groove.