Disclosed are an air shower with a foam jetting function and a clean room system. The air shower with the foam jetting function comprises an air supply device, an air suction device, a control device,a chamber, handrails and an elevated floor. The air supply device further comprises a foam box, a static electricity generation device is arranged at the bottom of the foam box, an S-shaped pipe is connected to the lower end of the foam box, and the other end of the S-shaped pipe communicates with an air inlet pipe of the air supply device. Clean foam particles are placed in the foam box, the foam particles are round or cylindrical, and the foam particles are high resilience polyurethane foam particles. The air shower with the foam jetting function can spray out the soft foam particles, and thus the effects of physical patting and electrostatic adsorption are improved, certain interestingness and stimulating massage functions are achieved, a good air showering effect can be obtained at alower air speed, anxiety generated when people wait in a high-noise and high-air-speed environment during air showering is reduced, and the problem that part of stubborn dust is difficult to remove under established wind force is solved.