The invention discloses a directional controlled blasting hole layout method for a cliff. The method comprises the following steps that firstly, remote control commanding and air circling camera shooting and photographing functions of an unmanned aerial vehicle are utilized to obtain a size-calibrated top view image of the landform of the to-be-exploded cliff; and a design of directional controlled blasting holes is carried out on the size-calibrated top view image of the cliff, then on-site layout and real-time monitoring analysis of the blasting holes are carried out through the unmanned aerial vehicle, so that drilling can meet the design requirements, and directional controlled blasting of the cliff can be realized. According to the directional controlled blasting hole layout method for the cliff, the defect of incapability of contact measurement can be overcome, the design of the directional controlled blasting holes can be carried out on the size-calibrated top view image, the hole positions, directions, depths and the like of the drilling can meet design requirements, and directional controlled blasting of the cliff where on-site measurement is hard and approach of drillingand blasting equipment is hard is achieved.