The invention relates to a highway vehicle speed calculation method based on mobile phone signaling big data, and belongs to the field of intelligent traffic. The method concretely comprises the stepsthat grid division is performed to construct a geographic grid system according to the highway route, the base station information table of the highway is acquired and an information table in which the base station and the road grid are matched is constructed; the mobile network mobile phone signaling data stream is acquired in real time, and effective travel segment division is performed after data preprocessing; highway user identification is performed; and finally the distance and the time of every two trace points of each user of a highway user trace sequence information set are extracted, and the vehicle speed is calculated through a distance weighted speed calculation method. The development of the road network monitoring system of the traffic management department can be greatly facilitated, and the traffic state of the road network can be acquired in real time so that the route can be reasonably planned, and the method is significant for improving the resident travel service.