The invention relates to an APP (application) method for using a smart terminal to realize picture taking and disease diagnosis. The method includes the following steps that: a user installs a picturetaking and disease diagnosis APP (application) on the smart terminal, after the user logs in the APP, the user can input the physical discomfort of the user and the requests of current picture takingand disease diagnosis; the picture taking and disease diagnosis APP (application) indicates a picture taking position by using texts, or an image-text form, or an animation and text combined form, and the user takes a picture of his or her body; the picture taking and disease diagnosis APP amplifies the picture taken by the user to a fixed scale and displays the picture, so that the user can viewthe picture, or a sample picture is additionally provided, so that the picture taken by the user and the sample picture can be viewed and compared with each other by the user; and the user checks thepicture and confirms that the picture satisfies a requirement, makes a position reflected by the taken picture consistent with an indicated position, and uploads the taken picture to a computer diagnosis server for disease diagnosis. The user is guided to take correct pictures according to the requirements of the six-diagnosis method of the traditional Chinese medicine; and the sample picture isprovided as a reference, and a reference object is included in the picture. The picture taking and disease diagnosis APP (application) method of the invention needs to be matched with the computer diagnosis server so as to realize disease diagnosis according to the picture. With the APP adopted, contribution can be made to the early prevention and early treatment of diseases.