The invention discloses chews inlaid with granular meat. The chews consist of derma fibers and granular meat, wherein the granular meat is inlaid in the derma fibers and the granular meat and the derma fibers are formed into an integral structure. The disadvantages that conventional dog chews are poor in palatability, the chews are wrapped with meat, so that dogs like to eat meat parts and chew parts are remained are, overcome. The utilization rate of skin resources is greatly increased, the waste of skin scraps is reduced, and the chews have extremely high social value and economic value. Theinvention further discloses a preparation method of the chews inlaid with granular meat.