The invention provides a multilevel coordination regulation management method capable of ensuring power supply, and belongs to the field of power supply. The management method includes: acquiring abnormal alarm information found by a monitoring device, and allowing a regulation center to determine an operation and maintenance worker corresponding to the abnormal alarm information to perform on-site inspection; allowing the operation and maintenance worker to acquire fault information, reporting the fault information to the regulation center to perform analysis and determination, allowing the regulation center to determine an emergency disposal scheme, and allowing the operation and maintenance worker to perform on-site accident emergency maintenance according to the emergency disposal scheme; and writing an accident analysis report and performing filing after maintenance. The regulation management scheme can form an effective power-off disposal scheme during an important activity or animportant event, can improve the disposal efficiency of a power-off accident, and can reduce influence due to power-off time.