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发明授权
CN108218925B 咪唑并吡啶类化合物钴配合物及其应用 有权

咪唑并吡啶类化合物钴配合物及其应用
摘要：
本发明涉及新型钴配合物——咪唑并吡啶类化合物钴配合物，含有这些配合物的组合物，及其在制备抗肿瘤药物中的应用。本发明的化合物结构如下式(I)所示：其中，R1选自H，C1‑C6烷基，C1‑C6烷氧基，羟基，氨基，卤素，氰基，硝基；R2选自H，取代或未取代的C1‑C6烷基，C1‑C6烷氧基；所述的取代基为C1‑C6烷基，C1‑C6烷氧基，卤代C1‑C6烷氧基；R3选自H，C1‑C6烷基，C1‑C6烷氧基，羟基，氨基，卤素。本发明的咪唑并吡啶类化合物钴配合物及其组合物可以用于制备抗肿瘤药物。
摘要（英）：

The invention relates to novel cobalt complexes, namely imidazopyridine compound cobalt complexes, composition containing the complexes, and application thereof to preparation of antitumor medicines.The structure of the compound is shown as a formula (I) as follows: FORMULA, wherein R1 is selected from H, C1-C6 alkyl, C1-C6 alkoxy, hydroxy, amino, halogen, cyano and nitro; R2 is selected from H,substituted or unsubstituted C1-C6 alkyl and C1-C6 alkoxy; a substituent is C1-C6 alkyl, C1-C6 alkoxy and halogenated C1-C6 alkoxy; R3 is selected from H, C1-C6 alkyl, C1-C6 alkoxy, hydroxy, amino andhalogen. The imidazopyridine compound cobalt complexes and the composition thereof can be applied to preparation of the antitumor medicines.

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