The invention relates to a nanofiber reinforced fluoride-containing ion exchange membrane and a preparation method thereof, and belongs to the technical field of preparation of composite membranes. The nanofiber reinforced fluoride-containing ion exchange membrane consists of a fluoride-containing ion exchange membrane base layer, at least one nanofiber layer and at least one fluoride-containing ion exchange membrane coating layer, wherein the nanofiber layer is positioned on one side or two sides of the fluoride-containing ion exchange membrane base layer; the fluoride-containing ion exchangemembrane coating layer is positioned on the nanofiber layer. The prepared fluoride-containing ion exchange membrane has high mechanical strength and good ion conductivity; the nanofiber layer has thecharacteristics of adjustable pore size and fiber diameter, high porosity and the like. The invention further provides the preparation method thereof. The preparation method comprises three steps; bythe preparation method, a technology is simple, scientific and reasonable, and operation is convenient.