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发明公开
CN108289931A 4’-取代的核苷逆转录酶抑制剂及其制备 有权 转让

4’-取代的核苷逆转录酶抑制剂及其制备
摘要：
本发明涉及式(I)的4’-取代的核苷衍生物及其在抑制HIV逆转录酶、预防HIV感染、治疗HIV感染和预防、治疗和延迟AIDS和/或ARC发作或进展中的用途。本发明还提供了制备式(I)的4’-取代的核苷衍生物及其衍生物的方法。
摘要（英）：

The present invention is directed to 4'-substituted nucleoside derivatives of Formula (I) and their use in the inhibition of HIV reverse transcriptase, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS and/or ARC. The present invention also provides processes for the preparation of 4'-substituted nucleoside derivatives of Formula (I) and derivatives thereof.

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