The invention discloses a disinfection and drying device of medical equipment. The disinfection and drying device comprises a base, wherein supporting legs are fixed at the bottom of the base; a disinfection box and an open source single chip microcomputer are arranged at the top of the base respectively; an electric door is mounted at a box opening of the disinfection box; a net bag is connectedwith the inner side of the disinfection box through a driving device; the net bag is in sliding connection with the disinfection box through a sliding mechanism; a drying device is mounted at the bottom of the disinfection box; a disinfection device is mounted on a side face of the disinfection box. According to the disinfection and drying device of the medical equipment, high-pressure steam is generated by the disinfection device so that the medical equipment is disinfected; the driving device drives the net bag to rotate so that the contact speed of the steam and the medical equipment is improved and the disinfection efficiency is greatly improved; meanwhile, the medical equipment also can be washed by spraying the steam on the medical equipment; the net bag is in sliding connection withthe disinfection box through the sliding mechanism so that the rationality of the design is ensured.