The present invention discloses a photovoltaic power station monitoring and operation integration system. The technical scheme of the invention concretely comprises the steps of: detecting generationcurrents and voltages of photovoltaic cells through a Hall sensor in photovoltaic combiner boxes and transmitting the generation currents and voltages to a processor; connecting and gathering detection modules of the plurality of combiner boxes in a RS485 communication mode to perform transmission through a wireless module; determining a photovoltaic panel fault condition through a photovoltaic panel fault rapid detection location system based on an unmanned aerial vehicle; monitoring and cleaning a photovoltaic panel through a cleaning robot carrying a dust detection sensor; locating actual positions of faults through the photovoltaic panel fault rapid detection location system based on the unmanned aerial vehicle, and sending fault information through a wireless communication module; andapplying the wireless communication network to connect each system of a power station to allow operation and maintenance work to be integrated and intelligent.