The invention relates to a lacrimal passage trephine unimpeded catheter system, and is mainly used for having an operation on a human ocular region lacrimal passage. An existing therapeutic method ishigh in cost, cumbersome, damaging in bone wall, easy in adhesion and extreme low in success rate. By adopting the method, when the lacrimal passage is blocked, the steps of a combined probe probing into the lacrimal passage->proving blockages->injecting water to verify block->annularly cutting the blockage by a trephine->injecting water to verify an unobstructed lacrimal passage->placing a lowercatheter, are performed, the probing and trephining are integrally and constantly completed, the operation is simple and convenient, and the trephining is accurate to avoid damaging tissues due to multiple treatment; the trephine with a protecting core can be used as the probe, when the protective core is pulled out, the trephine can be used as a trephine knife, so that skin incisions do not appear during an operation, and the blockages in any part of the lacrimal passage can be thoroughly and annularly cut; the tail portions of upper and lower catheters are tied by a connecting string, the lacrimal punctum cannot be easily cracked, and the catheters cannot easily penetrate out of a palpebral fissure; after the operation, a silicone flexible tube can be conveniently and movably implanted into the lacrimal passage, and it can be avoided that catheter implanting for a long time leads to adhesion with tissues.