The invention discloses a female genital cleaning and care solution. The female genital cleaning and care solution is prepared from the following components: 10 to 15 parts of chitosan quaternary ammonium salt hydrogel, 10 to 25 parts of itching stopping agent, 6 to 12 parts of inorganic nano antibacterial agent, 4 to 7 parts of nano lecithin and 20 to 35 parts of auxiliary agent. The cleaning andcare solution disclosed by the invention can be used for absorbing tissue fluid oozed from skin with inflammations and also can have remarkable antibacterial, anti-inflammation and repairing-promoting effects; the cleaning and care solution is easily absorbed in a percutaneous manner through an external bathing manner and genitals keep clean and sanitary; the cleaning and care solution also can be used for preventing and treating genital flora imbalance and reducing the risk of bacterial genital diseases; the multi-effects of cleaning, nutrition, sterilization and care are realized.