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发明公开
CN108348468A 具有生物活性亲脂性化合物的聚乙二醇化脂质纳米粒 审中-实审

具有生物活性亲脂性化合物的聚乙二醇化脂质纳米粒
摘要：
本发明涉及用于全身或局部递送亲脂性诊断或治疗剂到有需要的个体的纳米粒。本发明的纳米粒包含水溶性聚合物以及生物相容性脂质和亲脂剂中的至少一种。本发明还涉及使用本发明的纳米粒的眼科治疗。此外，本发明涉及包含本发明的纳米粒的组合物和制剂。这样的制剂可以是滴眼剂制剂。
摘要（英）：

The invention relates to nanoparticles for the systemic or topical delivery of lipophilic diagnostic or therapeutic agents to a subject in need thereof. The nanoparticles of the invention comprise a water soluble polymer and at least one of a biocompatible lipid and a lipophilic agent. The invention further relates to ophthalmic treatment using the nanoparticles of the invention. In addition, the invention pertains to compositions and formulations comprising the nanoparticle of the invention. Such formulation may be an eye drop formulation.

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