An embodiment of the invention provides a regular interference suppressing method and device. The method includes acquiring a shot gather record of irregular sampling seismic data; determining the apparent velocity maximal average time difference and the apparent velocity minimal average time difference of adjacent seismic channels in the shot gather record; extracting regular interference area data in the shot gather record according to the apparent velocity maximal average time difference and the apparent velocity minimal average time difference; determining a frequency space domain regularinterference filtering operator; converting the frequency space domain regular interference filtering operator to a time domain regular interference filtering operator; performing filtering suppressing on the regular interference area data according to the time domain regular interference filtering operator and obtaining suppressed seismic data. According to the invention, regular interference canbe suppressed, and amplitude characteristic can be kept well, so that an aim of improving seismic data signal to noise ratio and resolution can be achieved at the same time of suppressing regular interference.