The invention discloses a tower crane anti-swing operation control method. The method comprises the steps that crane operating parameters are input; the crane transport time is equally divided into Nsegments, an accelerated speed curve on each segment is approached through a one-time straight line method, and a state curve is calculated through a four-step Runge-Kutta method; and an SQP optimization algorithm is adopted to optimize the control parameters of the segmented straight line, and the optimal accelerated speed control curve is obtained.