The invention discloses a disinfection cabinet. The disinfection cabinet comprises an air purifying box and a cabinet body. The air purifying box is fixedly mounted at the top end of the cabinet body,and an air inlet is formed in the middle end of the left side of the air purifying box. An inner cavity of the air purifying box is sequentially connected with a polypropylene filtering screen layer,a particle filtering screen layer, an activated carbon filtering layer, a plasma generator and a draught fan from left to right. An air outlet is formed in the middle end of the right side of the airpurifying box. According to the disinfection cabinet, an ultraviolet disinfection chamber is formed in the upper end of an inner cavity of the cabinet body, a high-temperature disinfection chamber isformed in the lower end of the inner cavity of the cabinet body, and ultraviolet disinfection and high-temperature disinfection treatment on objects can be achieved through the functions of ultraviolet lamp tubes and heating tubes. The disinfection effect of the disinfection cabinet on the objects is effectively improved, and the problems that an existing disinfection cabinet is provided with only one disinfection chamber, the need of people for disinfection on certain special objects cannot be met, and inconvenience is brought to use by people are solved.