The invention provides a full-automatic laser marking and cable marker threading device. The device comprises a device working platform, a cable marker conveying platform, a laser marking device, a marking cutting tool, a cable marker penetrating device and a controller, wherein the cable marker conveying platform, the laser marking device, the electric cutting tool, the cable marker penetrating device and the controller are arranged at the upper part of the device working platform; a cable marker conveying roller wheel, a servo motor, a guide tube and a guide tube bracket are arranged at theupper part of the cable marker conveying platform; the electric cutting tool consists of a cable marker cutting tool rack and a cable marker cutting blade; the cable marker penetrating device comprises a cable marker clamp, a first horizontal sliding platform, a second horizontal sliding platform, a wire tube support and a wire tube. The device is high in intelligence degree and is capable of automatically performing laser marking and threading on the cable marker.