The invention provides a relay protection active anti-error method for an intelligent transformer substation, and the method comprises the steps: carrying out the state diagnosis of a relay protectiondevice, and determining whether the relay protection device is in a normal state or not; judging whether a pressing plate state of the relay protection device, a related device state and the operation state of primary equipment are matched with the state rules corresponding to the normal state or not when the relay protection device is in an abnormal state, and finding an abnormal pressing plate;carrying out the operation rehearsing of the abnormal pressing plate, transmitting a corresponding operation instruction after the successful rehearsing, executing the operation instruction, and enabling the relay protection device to enter a normal state. The method solves problems that a relay protection active anti-error method for the intelligent transformer substation in the prior art is notcomplete in abnormal analysis and is not high in reliability.