The embodiment of the invention discloses a voice call data processing method, a voice call data processing device, a storage medium and a mobile terminal. The method comprises the steps of: after a voice call group in a pre-set application is established successfully, obtaining first voice data acquired by the microphone of the mobile terminal in the current time period; when the fact that an anti-squeal processing event is triggered is detected, performing voice and background sound separation operation on the first voice data, and weakening the separated background sound; and, performing sound mixing on the weakened background sound and the separated voice, so that first uplink voice call data is obtained, and sending the first uplink voice call data to a server corresponding to the pre-set application. By adoption of the technical scheme in the invention, after the voice call group of the pre-set application in the mobile terminal is established successfully and the fact that the anti-squeal processing event is triggered is detected, anti-squeal processing on the uplink voice call data of the current mobile terminal is carried out in time.