A detoxifying composition for oral administration, characterised in that it comprises dried inflorescence stems from the pepper plant, that are optionally ground and optionally sieved, and/or a liquid or dry extract of pepper plant inflorescence stems. The pepper plant inflorescence stems are advantageously chosen from inflorescence stems from the Piper nigrum or Piper longum pepper plants, in particular from the Kampot region of Cambodia. The food composition or supplement or fortified foodstuff or dietary product containing same is used in order to promote the elimination of waste from the organism, in particular by the liver.